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Conclusions are published after independent cross-review.

MRKMerck & Co., Inc.
—Full research page

Verdict

Automated coverage for Merck & Co., Inc.. Sector: Health Care. Pending deep research for full thesis.

Change history

  • Jun 9View held

    FDA Breakthrough Therapy designation for calderasib (MK-1084) + KEYTRUDA in first-line KRAS G12C-mutant NSCLC (2026-05-29); catalyst/monitoring status hygiene

  • May 20View held

    Fianlimab + Libtayo Phase 3 Harmony Melanoma trial failed primary endpoint vs Keytruda (pembrolizumab) head-to-head

Watching

  • TD Cowen 46th Annual Health Care ConferenceMar 3126d ago
  • Second-quarter 2026 ex-dividend dateMar 16113d ago
  • FDA PDUFA date for KEYTRUDA/KEYTRUDA QLEX plus Padcev in cisplatin-ineligible MIBCApr 791d ago
  • FDA PDUFA date for doravirine/islatravir NDA (approved Apr 21, 2026 as IDVYNSO)Apr 2870d ago
  • Q1 2026 earnings callApr 3068d ago
  • FDA Breakthrough Therapy designation for calderasib (MK-1084) + KEYTRUDA in first-line KRAS G12C-mutant NSCLCMay 2939d ago

Latest notes

  • Jun 9Update — FDA Breakthrough Therapy designation for calderasib (MK-1084) in first-line KRAS G12C NSCLC
  • May 20Update — Keytruda head-to-head win vs REGN fianlimab + Libtayo in first-line melanoma
  • Mar 13Lite Research: MRK — S&P 500 coverage

Exposure

1-hop
Suppliers
  • BMY
Customers
  • MCKPharmaceutical wholesale distribution
  • CORPharmaceutical wholesale distribution
  • CAHPharmaceutical wholesale distribution

Options radar

Concept — illustrative data
  • Jun 30Call$110.00Aug 211,200 ct$540K
  • Jun 30Call$105.00Jul 17800 ct$216K
  • Jun 29Put$95.00Aug 21600 ct$168K
Unusual volume3.2x 20-day avg call volume
IV shift30-day IV 41% → 48%

Positioning skews toward near-term upside

FDA PDUFA date for KEYTRUDA/KEYTRUDA QLEX plus Padcev in cisplatin-eligible MIBC (KEYNOTE-B15)
Aug 17
in 41d
  • FDA PDUFA date for WINREVAIR HYPERION sBLASep 21in 76d
  • Calderasib (MK-1084) Phase III KANDLELIT readout / regulatory filing in first-line KRAS G12C-mutant NSCLC
  • KEYTRUDA U.S. revenue trajectory into the 2028 IRA pricing + compound patent cliff